2C-N (2,5-dimethoxy-4-nitrophenethylamine) is classified as an illegal Schedule I drug in the United States (as of 2012).
Addictive Potential: None
Emergency Room Visits Yearly: Unknown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: Active state-selective agonism of the 5-HT2A receptor
2C-N is also known as 2,5-Dimethoxy-4-nitrophenethylamine and 2,5-dimethoxy-4-nitro-β-phenethylamine. It is a psychedelic phenethylamine of the 2C family. 2C-N was first synthesized by Alexander Shulgin, and he wrote about the chemical in his book PiHKAL. According to Shulgin (1995), the oral dosage of 2C-N typically ranges from 100 – 150 mg, and the duration of effects lasts for 4 – 6 hours. As recounted by Shulgin, the effects of 120mg “came on very fast–I was aware of it within a half hour, and it got as far as it would go by an hour. There are similarities to MDMA, but missing is the benign anti-stress component. I am light-headed, and there just might be a little eye wiggling. And then it dropped right off to nothing within a couple of hours.”
Visual identification. Due to the “nitro” group within 2C-N, the powder will take on a bright yellow to orange color (Sirchie, 2014).
Side Effects and Adverse Reactions:
There is currently no empirical data about the side effects, adverse reactions, long term damage, and/or addiction potential of 2C-N. Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest the research chemical 2C-N, it is unreasonable to assume that it is in any way safe to use recreationally.
- Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine 5-HT 2A and 5-HT2C receptors
- Identification and characterization of 2, 5-dimethoxy-4-nitro-β-phenethylamine (2C-N)–a new member of 2C-series of designer drug
Other Informational Resources: