Saturday, April 29, 2017
Breaking News


4-Acetoxy-DET4-AcO-DET is currently Unscheduled in the United States. It is a gray area in the law because it may be illegal under the federal analog act.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Currently unknown, but likely to be a 5-HT2a agonist


4-AcO-DET is also known as 4-Acetoxy-N,N-diethyltryptamine, 4-Acetoxy-DET, ethacetin, and ethylacybin. Jebadurai (2013) wrote that recreational users report the effects of 4-AcO-DET as “similar to that of psilocybin, but at a very milder experience. Some users their dislike for this compound due to its lack of the ‘depth’ of experience and the ‘magic’ experience of mushrooms”. That said, some of the positive effects reported by users include euphoria, out of body experiences, and religious experiences/introspection (Jebadurai). Dosages are reported to range from 2 mg – 40 mg, and the duration of effects usually lasts from 2-5 hours (Erowid, 2009).

Substance Identification:

     PDMB Reagent Marquis Reagent      Mecke Reagent 
4-AcO-DET  Purple  Yellow to brown  Black

(Info provided by Morris, 2013)

Side Effects & Adverse Reactions:

There is limited empirical data about the side effects, adverse reactions, long term damage, and/or addiction potential of 4-AcO-DET. According to Jebadurai (2013), some of the potential negative effects include:

  • extreme anxiety during the peak
  • palpitation
  • increased body temperature
  • raised blood pressure
  • nausea
  • hypersalivation
  • reduced reaction of the pupils indicating mydriasis
  • increased reflexes
  • coordination disturbances
  • difficulty in speech articulation
  • dysphoria
  • restlessness
  • clouded consciousness

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest the research chemical 4-AcO-DET, it is unreasonable to assume that it is in any way safe to use recreationally.


Qualitative research of online drug misuse communities with reference to the novel psychoactive substances

More Info:

4-acetoxy-DET Primer

4-Acetoxy-DET / Ethacetin Degradation Investigation

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