Saturday, April 29, 2017
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4-Fluoroamphetamine

4-FA4-Fluoroamphetamine is currently unscheduled in the United States. However, this is a gray area of the law, which means it may be illegal via the federal analog act.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action:  Monoamine re-uptake inhibitor and releaser

Overview:

4-Fluoroamphetamine is also known as 4-FA, PAL-303, Flux, para-fluoroamphetamine (PFA),p-fluoro-alpha-methylphenethylamine, and 4-fluoro-alpha-methylphenethylamine. It is a research chemical in the phenethylamine and amphetamine classes of substances. 4-FA has been around since the 1960s. Although, it has only been used recreationally in recent years.

As for pharmacology, Nagai et al. (2007) found that 4-FA had “strong inhibitory effects on the re-uptake of dopamine, 5-HT, and norepinephrine”, and it also “strongly increased the release of the three monoamines”. Thus, 4-FA use can bring about stimulant and entactogenic effects. According to Jebadurai (2013), “Oral ingestion is the common mode of consumption”; still, some users also reported using the substance through nasal insufflation and intravenous injection. Users on Erowid have reported using 4-FA at oral dosages ranging from 50mg to 200mg with effects lasting up to 8 hours.

Substance Identification:

       Marquis Reagent Mecke Reagent
4-Fluoroamphetamine No Reaction No Reaction

(Info provided by EcstasyData)

Side Effects and Adverse Reactions:

There is currently limited empirical data about the side effects, adverse reactions, long term damage, and/or addiction potential of 4-fluoroamphetamine. That said,  Jebadurai (2013) reported the following negative effects were experienced by a portion of users:

  • Loss of appetite
  • Insomnia
  • Tachycardia
  • Psychosis
  • Hallucinations
  • Violent behavior

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest the research chemical 4-fluoroamphetamine, it is unreasonable to assume that it is in any way safe to use recreationally.

Deaths and Overdoses:

Research:

Other Informational Resources:

One comment

  1. Me and my friends used 4FA lots of times. As well as all the reports on the internet say:
    – Usually its taken orally in dosages between 120mg and 200mg.
    – You get a great euphoria like MDMA for about 3 hours or so…
    – You get a lots of energy for about 6 hours…
    – Total experience with comedown about 8 hours.
    – Its a really clear headed experience with almost no memory loss (like you get with MDMA or Alcohol)
    – Its an amazing party drug and lots of people prefer it over MDMA because of 1. the energy that comes with it. 2. no hangover and 3. great memories 🙂

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