Addictive Potential: Unknown
Emergency Room Visits Yearly: Unknown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: Monoamine re-uptake inhibitor and releaser
4-Fluoroamphetamine is also known as 4-FA, PAL-303, Flux, para-fluoroamphetamine (PFA),p-fluoro-alpha-methylphenethylamine, and 4-fluoro-alpha-methylphenethylamine. It is a research chemical in the phenethylamine and amphetamine classes of substances. 4-FA has been around since the 1960s. Although, it has only been used recreationally in recent years.
As for pharmacology, Nagai et al. (2007) found that 4-FA had “strong inhibitory effects on the re-uptake of dopamine, 5-HT, and norepinephrine”, and it also “strongly increased the release of the three monoamines”. Thus, 4-FA use can bring about stimulant and entactogenic effects. According to Jebadurai (2013), “Oral ingestion is the common mode of consumption”; still, some users also reported using the substance through nasal insufflation and intravenous injection. Users on Erowid have reported using 4-FA at oral dosages ranging from 50mg to 200mg with effects lasting up to 8 hours.
|Marquis Reagent||Mecke Reagent|
|4-Fluoroamphetamine||No Reaction||No Reaction|
(Info provided by EcstasyData)
Side Effects and Adverse Reactions:
There is currently limited empirical data about the side effects, adverse reactions, long term damage, and/or addiction potential of 4-fluoroamphetamine. That said, Jebadurai (2013) reported the following negative effects were experienced by a portion of users:
- Loss of appetite
- Violent behavior
Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest the research chemical 4-fluoroamphetamine, it is unreasonable to assume that it is in any way safe to use recreationally.
Deaths and Overdoses:
- Isomers of fluoroamphetamines detected in forensic cases in Denmark
- The role of stimulant designer drug consumption in three fatal cases in South-East Hungary in 2011
- Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs)
- Detection of the synthetic drug 4-fluoroamphetamine (4-FA) in serum and urine
Other Informational Resources: