Thursday, May 25, 2017
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44dimethylaminorex_structure4,4’-DMAR is currently unscheduled in the United States. However, this is a gray area of the law, which means it may be illegal via the federal analog act.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Unknown


4,4’-DMAR is also known as 4,4-dimethylaminorex, Serotoni, 4-methyl-euphoria, 4-methyl-U4Euh, para-methyl-4-methylaminorex, and 4-M-4-MAR. It is the para-methyl derivative of the stimulant drug 4-methylaminorex. Thus far, 4,4’-DMAR has been distributed as a powder and in pressed pills. According to Europol (2014), the substance was first detected in 2012; since then, it has emerged in Denmark, Finland, Hungary, the Netherlands, Sweden, and the United Kingdom.


These pills (Cherry logo and Cross logo) have been linked to deaths in Northern Ireland. Both types of pills contain 4,4’-DMAR.

Side Effects and Adverse Reactions:

There is currently limited empirical data about the side effects, adverse reactions, long term damage, and/or addiction potential of 4,4’-DMAR. Still, the EMCDDA (2014) reported a number of negative effects including:

  • agitation
  • hyperthermia
  • foaming at the mouth
  • breathing problems
  • cardiac arrest

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest the research chemical 4,4’-DMAR, it is unreasonable to assume that it is in any way safe to use recreationally.

Deaths and Overdoses:

In 2013, 8 deaths were reported in Hungary, and 18 deaths were reported in the UK. In many of these cases, 4,4’-DMAR appears to have been used in combination with other drugs (EMCDDA, 2014).


Other Informational Resources:

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