Thursday, May 25, 2017
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5-MeO-AMT5-MeO-AMT is unscheduled in the United States.  Although this is a gray area in the law because it may be illegal under the federal analog act.

Addictive Potential: None

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action:  Strongly inhibits the re-uptake and increases the release of dopamine, serotonin, and norepinephrine


5-MeO-AMT is also known as 5-methoxy-alpha-methyltryptamine, 5-methoxy-α-methyltryptamine, O-Dimethyl-Serotonin, Alpha-O-DMS, and Alpha-O.

5-MeO-AMT typically is consumed orally in 2 to 6 milligram dosages, although dosage amounts vary widely. It also may be administered via snorting or smoking. Users report feeling effects within 1 hour after administration, and these effects generally last for 12 to 14 hours.

Substance Identification:

     Ehrlich’s Reagent          Marquis Reagent    
5-MeO-AMT HCl purple to blue yellow to black

(Info provided by DEA, 2005)

Side Effects and Adverse Reactions:

Negative effects that have been reported include:

5-MeO-AMT also acts as an MAOI. According to MobileReference (2007), it provides “minor MAO inhibition”.

Furthermore, 5-MeO-AMT is a research chemical. Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.

Hospitalizations and Deaths:

5-MeO-AMT Hospitalizations & Possible Deaths


The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain

“Research Chemicals”: Tryptamine and Phenethylamine Use Among High-Risk Youth

More Information:

TiHKAL 5-Meo-AMT Entry

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