Saturday, March 25, 2017
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6-APB

6-APB_structure6-APB is currently Unscheduled in the United States. This is a gray area in the law because it may be illegal under the federal analog act.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: 5-HT(2C) and 5-HT (2b) receptor agonist

Overview:

6-APB, also called 6-(2-aminopropyl)benzofuran and Benzo-Fury, is a research chemical. Although there is a limited amount of current reports of this substance’s effects in humans, some users have experienced a stimulant and/or euphoric effect. Some have even compared it to the effects of MDMA. As well, users report the effects lasting for up to 12 hours, which is significantly different from the effects of MDMA which usually last only 4 – 6 hours (Bluelight, 2011).

Oral dosages are reported to range between 90 and 125 mg (Bluelight, 2011).

Substance Identification:

     Mecke Reagent          Marquis Reagent    
6-APB  Purple  Purple

(Info provided by Morris, 2012)

Side Effects and Adverse Reactions:

Users have reported stimulant-like side effects such as increased heart rate, high  blood pressure, and tightness in the chest along with:

  • Sweating
  • Nystagmus – involuntary eye movement from side to side
  • Dry mouth
  • jaw tension, grinding
  • Warm extremeties, mild parasthesia, or tingling
  • Jitteriness
  • Wobbly walking, rubbery legs
  • Difficulty urinating
  • Nausea, vomiting
  • Headaches
  • Insomnia
  • Diarrhea the day or two after use

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.

Videos:

Research:

 US Patent Pharmacology Info

Acute Psychosis Associated with Recreational Use of Benzofuran 6-(2-Aminopropyl) Benzofuran (6-APB) and Cannabis

Neurochemical profiles of some novel psychoactive substances

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