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a-PVP (Flakka)

Alpha-Pyrrolidinopentiophenonea-PVP is is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute without a DEA license. Not available by prescription.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Unknown


Flakka seized by Broward County Florida police on May 28, 2015.

Flakka seized by Broward County Florida police on May 28, 2015.

a-PVP is also referred to as flakka, gravel, O-2387, and alpha-pyrrolidinopentiophenone.  It is a synthetic cathinone with euphoric and stimulant effects that are similar to MDPV.

a-PVP takes the form of a white or pink, foul-smelling crystal that can be eaten, snorted, injected, or vaporized in an e-cigarette or similar device. Vaporizing, which sends the drug very quickly into the bloodstream, may make it particularly easy to overdose. Like other drugs of this type, alpha-PVP can cause a condition called “excited delirium” that involves hyperstimulation, paranoia, and hallucinations that can lead to violent aggression and self-injury. The drug has been linked to deaths by suicide as well as heart attack. It can also dangerously raise body temperature and lead to kidney damage or kidney failure.

Substance Identification:

             Mecke Reagent  Marquis Reagent   
a-PVP  Black  Clear

(Info provided by Reagent-base)

Side Effects & Adverse Reactions:

a-PVP is a research chemical, and little is known about its long term damage and/or addiction potential. Some of the negative effects of a-PVP include:

  • hyperstimulation
  • paranoia
  • hallucinations
  • violent aggression
  • self-injury

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest the drug a-PVP, it is unreasonable to assume that it is in any way safe to use recreationally.



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