Saturday, April 29, 2017
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Alprazolam (Xanax)

xanaxXanax is Schedule IV in the United States. This means it is illegal to sell without a DEA license and illegal to buy or possess without a license or prescription.

Addictive Potential: Medium

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Not more than 3 years

Mechanism of Action: Increases the Neurotransmitter GABA(A)


Alprazolam is a short-acting drug in the benzodiazepine class used to treat anxiety disorders and as an adjunctive treatment for depression. It is also used as a medication to aid the beginning of treatment with SSRI type drugs, since these can cause anxiety in the initial stages of use.

Alprazolam was first synthesized by Upjohn (now a part of Pfizer) and is marketed under various trade names. Its patent was filed on October 29, 1969, granted on October 19, 1976 and expired in September 1993.

Alprazolam is a triazolobenzodiazepine, that is, a benzodiazepine with a triazolo-ring attached to its structure. Benzodiazepines produce a variety of effects by modulating the GABA(A) subtype of the GABA receptor, the most prolific inhibitory receptor within the brain.

Brand Names:

  • Aceprax® – Uruguay
  • Afobam® – Poland
  • Alplax® – Argentina
  • Alpralid® – Israel
  • Alpravecs® – Italy
  • Alprax® – India
  • Alprazig® – Italy
  • Alprox® – Finland
  • Alviz® – Indonesia
  • Alzolam® – India, Malaysia
  • Apo-Alpraz® – Canada (also made by other companies under different names)
  • Apraz® – Brazil
  • Azor® – South Africa
  • Calmax® – Ireland
  • Constan® – Japan
  • Dormonoct® – Portugal
  • Farmapram® – Mexico
  • Frontal® – Brazil, Italy
  • Frontal XR® – (an extended release formulation) Brazil
  • Frontin® – Hungary, Slovak Republic, Czech Republic
  • Helex® – Croatia, Slovenia
  • Jialeding® (佳乐定)- China
  • Kalma® – Australia
  • Kinax® (景安寧) – Taiwan
  • Ksalol® – Serbia
  • Manorest® – Sri Lanka
  • Mialin® – Italy
  • Misar® – Croatia
  • Neurol® – Czech Republic, Slovak Republic
  • Niravam® – (formulation that dissolves on the tongue) United States
  • Paxal® – Iceland
  • Ralozam® – Australia
  • Restyl® – Bahrain, Cyprus, Egypt, India, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Oman, Qatar, Republic of Yemen, Saudi Arabia, Syria, United Arab Emirates
  • Sedipral® – Paraguay
  • Solanax® – Japan
  • Tafil® – Austria, Costa Rica, Germany, Mexico, Portugal, Switzerland, Venezuela
  • Trankimazin® – Spain
  • Xanax XR® – (an extended release formulation) Israel, United States, Portugal
  • Xanax® – Australia, Belgium, Bulgaria, Croatia, France, Germany, Greece, Hungary, Ireland, Italy, Netherlands, New Zealand, Pakistan, Poland, Portugal, Romania, Serbia, Singapore, Slovak Republic, Switzerland, Turkey, United Kingdom, United States
  • Xanor® – Austria, Finland, Norway, Philippines, South Africa, Sweden
  • Xanor SR® – (slow release) South Africa
  • Zamhexal® – Australia
  • Zolarem® – Bahrain, Benin, Burkina-Faso, Cyprus, Egypt, Ethiopia, Gambia, Ghana, Guinea, Iran, Iraq, Israel, Ivory Coast, Jordan, Kenya, Kuwait, Lebanon, Liberia, Libya, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Oman, Qatar, Republic of Yemen, Saudi Arabia, Senegal, Seychelles, Sierra-Leone, South Africa, Sudan, Syria, Tanzania, Tunisia, Uganda, United Arab Emirates, Zambia, Zimbabwe
  • Zoldac® – Benin, Burkina-Faso, Ethiopia, Gambia, Ghana, Guinea, India, Ivory Coast, Kenya, Liberia, Malawi, Mali, Mauritania, Mauritius, Morocco, Niger, Nigeria, Senegal, Seychelles, Sierra-Leone, South Africa, Sudan, Tanzania, Tunia, Uganda, Zambia, Zimbabwe
  • Zomiren® – Poland

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