Addictive Potential: Unknown
Emergency Room Visits Yearly: Unknown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: Cannabinoid receptor agonist
JWH-018 (1-pentyl-3-(1-naphthoyl)indole) is an analgesic chemical from the naphthoylindole family, which acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. JWH-018 is used in basic scientific research to identify cannabinoid receptors in the brain and study Δ9-THC’s mechanisms of action. According to the DEA (2009), “Based on the structural analysis, JWH-018 is not categorized as a THC substance, and is not similar in chemical structure to other substances controlled under the CSA.” The average dose is around 2-5mg smoked and the effects usually last for 1-3 hours.
(Info provided by Morris, 2012)
Side Effects and Adverse Reactions:
JWH-018 is a research chemical. Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.
JWH-018 and Drug Tests:
JWH-018 can be detected with drug tests from the redwood toxicology laboratory. The test checks for JWH-018 and JWH-073 metabolites in the urine with a window of detection up to 72 hours (depending on usage/dosage).