JWH-073 was emergency scheduled into schedule I category on March 1, 2011 in the United States, making it illegal to possess and distribute.
Addictive Potential: Unknown
Emergency Room Visits Yearly: Unknown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: Cannabinoid receptor agonist
Derived from the aminoalkylindole WIN 55,212-2, JWH-073 is an analgesic chemical from the naphthoylindole family. It acts as a cannabinoid agonist at both the CB1 and CB2 receptors. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, which results in a CB1:CB2 ratio of 0.23. JWH-073 is used in basic scientific research to identify cannabinoid receptors in the brain and study Δ9-THC’s mechanisms of action. According to the DEA (2009), “Based on the structural analysis, JWH-073 is not categorized as a THC substance, and is not similar in chemical structure to other substances controlled under the CSA.” The average dose is around 4-10mg smoked and the effects usually last for 1-2 hours.
JWH-073 is a research chemical. Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.
JWH-073 and Drug Tests:
JWH-073 can be detected with drug tests from the redwood toxicology laboratory. The test checks for JWH-018 and JWH-073 metabolites in the urine with a window of detection up to 72 hours (depending on usage/dosage).