Saturday, March 25, 2017
Breaking News


jwh081JWH-081 is Unscheduled in the United States.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Cannabinoid receptor agonist


JWH-081 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is fairly selective for the CB1 subtype, with affinity at this subtype approximately 10x the affinity at CB2. The average dose is around 3-8mg smoked and the effects usually last for 2-3 hours.

*View and Submit Your Experiences in the Community Trip Reports Area*

Side Effects and Adverse Reactions:

JWH-081 is a research chemical. Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.

JWH-081 and Drug Tests:

JWH-081 is a synthetic cannabinoid that currently cannot be detected with drug tests. This is because of how drug tests work. The basic concept is that your body attempts to break down any drugs you ingest. Metabolites are formed as part of this process; testing looks for the specific types of metabolites that could only occur as a result of drug taking. There is currently (as of Nov, 2009) no test that tests for the metabolites of synthetic cannabinoids. Rumor has it that scientists are developing a drug test that tests for them, although, the development and implementation process could take years.

Experience Reports:

JWH-081 Experience

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