Saturday, April 29, 2017
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DiethyltryptamineDET is currently Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute without a DEA license. Not available by prescription.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: ??


DET, also known as N,N-diethyltryptamine and 3-(2-Diethylaminoethyl)indole, is a hallucinogenic tryptamine with a duration of effects ranging from 2 to 4 hours. According to Böszörményi (1959), “DET can be best likened to a moderate mescaline intoxication, although in some features it resembles the LSD effect”. Specifically, some of these subjective effects reported include distortions in the experience of time, visual hallucinations, elation, and overall feelings of intoxication (Barceloux, 2012).

In the 1960s, DET was studied as a potential treatment for chronic alcoholism. However, researchers concluded that DET appeared to have “limited therapeutic value” (Faillace at al., 1970).

Side Effects & Adverse Reactions:

Negative effects that have been reported include:

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest research chemicals, it is unreasonable to assume that they are in any way safe to use recreationally.


Psychological Effects and Metabolism of N,N-diethyltryptamine in Man

Observations on the psychotogenic effect of NN diethyltryptamine, a new tryptamine derivative

Behavioral effects of N, N-diethyltryptamine: Absence of antagonism by xylamidine tosylate

The effect of diethyltryptamine and its derivatives on monoamine oxidase

Clinical evaluation of some hallucinogenic tryptamine derivatives

Hallucinogenic Drugs in the Treatment of Alcoholism: A Two-year Follow-up

The comparative behavioral effects of N,N-dimethyltryptamine and N,N-diethyltryptamine in primate dyads

More Information:

TiHKAL Entry on DET

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