Sunday, April 20, 2014
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Mucuna pruriens

mucuna_pruriensMucuna pruriens is Uncontrolled in the United States, however, it is not approved for human consumption. This is a gray area of the law because it contains, DMT, which is a Schedule I.

Addictive Potential: Unkown

Emergency Room Visits Yearly: Unkown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: increases dopamine and serotonin

Overview:Mucuna_pruriens_(Khajkuiri)_in_Kawal

Mucuna pruriens seeds contain high concentrations of levodopa, a direct precursor of the neurotransmitter dopamine. It has long been used in traditional Ayurvedic Indian medicine for diseases including Parkinson’s Disease. In large amounts (e.g. 30 g dose) it has been shown to be as effective as pure levodopa/carbidopa in the treatment of Parkinson’s Disease, but no data on long-term efficacy and tolerability is available. In addition to levodopa, Mucuna also contains serotonin (5-HT), 5-HTP, nicotine, N,N-DMT (DMT), bufotenine, and 5-MeO-DMT. As such, it could potentially have psychedelic effects, and it has purportedly been used in ayahuasca preparations. The mature seeds of the plant contain about 3.1-6.1% L-DOPA, with trace amounts of 5-hydroxytryptamine (serotonin), nicotine, DMT-n-oxide, bufotenine, 5-MeO-DMT-n-oxide, and beta-carboline. One study using 36 samples of the seeds found no tryptamines present in them. The leaves contain about 0.5% L-DOPA, 0.006% dimethyltryptamine (DMT), 0.0025% 5-MeO-DMT and 0.003% DMT n-oxide.

Research:

Presence of Compounds in Nescafé (Mucuna pruriens)

Medicinal Plants (Google Book Search)

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