Monday, March 27, 2017
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mescaline_2d_3dMescaline (3,4,5-trimethoxyphenethylamine) is a Schedule I in the United States. This means that it is illegal to manufacture, buy, possess, or distribute without a DEA license.

Addictive Potential: None

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Binds to and activates the serotonin 5-HT(2A) receptor


Mescaline is also known as 3,4,5-trimethoxyphenethylamine. It is a naturally occurring psychedelic alkaloid of the phenethylamine class, and it is the active constituent in PeyoteSan Pedro, and Peruvian Torch. According to Shulgin (2009), the psychoactive dosage of mescaline ranges from 200-400 mg (as the sulfate salt) and 178-356 mg (as the hydrochloride salt), and the effects usually last for 10-12 hours. Mescaline’s effects are similar to that of the LSD and psilocybin with users reporting vivid visual hallucinations (Thale et al., 1950).

Substance Identification:

     Mandelin Reagent          Marquis Reagent     Mecke Reagent   
Mescaline HCl Dark yellowish brown Strong orange Moderate olive

(Info provided by DOJ, 2014)

Side Effects & Adverse Reactions:

Some of the negative effects of mescaline include:

Deaths and Overdoses:



Additional Resources:

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