Methylone

 
Methylone 3D Molecule

Methylone was emergency scheduled into Schedule I category on October 21st, 2011 in the United States.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Unknown

 

Overview:

Methylone, bk-MDMA, is a psychoactive drug of the phenethylamine, amphetamine, and cathinone chemical classes that acts as an entactogen, psychedelic, and stimulant. It is the β-keto analogue of 3,4-methylenedioxy-N-methylamphetamine (MDMA).

At the end of 2004, a new designer drug called "Explosion" appeared in the Netherlands. This new drug is sold as a liquid via the internet and in Dutch "smartshops", stores selling non-scheduled psychoactive substances. The product is advertised as a "room odorizer" and is sold in plastic tubes containing 5 ml of liquid. The tubes cost between €10 and €15 ($13–$20) and do not present any information about the composition of Explosion; they contain only a label saying "Room odorizer Vanilla. Do not ingest" and "Keep away from children. Never use more than one bottle". In spite of this label, users mention that they ingest the liquid to reach the intended psychoactive effect. Analysis of "Explosion" have demonstrated that the main ingredient of the liquid was methylone.

Reported dosages range from 150 to 200 mg orally. The most users report experiencing euphoria and a strong sense of empathy and bonding. According to Shulgin, "[MDMC] has almost the same potency of MDMA, but it does not produce the same effects. It has an almost antidepressant action, pleasant and positive, but not the unique magic of MDMA."

 

Side Effects and Adverse Reactions:

Methylone is a research chemical. Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.

 

Research:

Inhibition of plasma membrane monoamine transporters by b-ketoamphetamines

Cathinone: An Investigation of Several N-Alkyl and Methylenedioxy-Substituted Analogs

Metabolism of the recently encountered designer drug, methylone, in humans and rats

Methcathinone and 2 methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (methylone) selectively inhibit plasma membrane catecholamine reuptake transporters

Feds Emergency Schedule Methylone

 

E-books:

The NeuroSoup Trip Guide - The free e-book version of The Neurosoup Trip Guide is now available online. It contains chapters on Choosing the Right Hallucinogen; Set, Setting, and Preparation for a Trip; Tips for Tripsitters; Aspects of the Entheogenic Experience; Working with Difficult Experiences; Integration; and References and Recommended Reading.

 

More Info:

Visit the New Community Trip Reports Area

How to Work With Bad Trips

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