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NBOMe List

The series of NBOMe chemicals are currently Unscheduled in the United States. It is a gray area in the law because they may be covered under the analog act.

Addictive Potential: Unknown

Emergency Room Visits Yearly: Unknown

Mandatory Minimum Sentence: Unknown

Mechanism of Action: Most are 5-HT(2A) receptor agonists or partial agonists


The NBOMe series of research chemicals began being prevalent across United States in 2010. Since the dosage ranges within the microgram level, substances within this series of chemicals have been utilized illicitly as a fake LSD (Bunk Police, 2011). Very little is known about the long-term effects, safety profile, and addictive potential of this series of drugs.

A partial list of the NBOMe series:

  • 24-NBOMe
  • 2C-B-NBOMe (25B-NBOMe)
  • 2CBFly-NBOMe
  • 2C-C-NBOMe (25C-NBOMe)
  • 2C-D-NBOMe (25D-NBOMe)
  • 2C-E-NBOMe
  • 2C-I-NBOMe (25I-NBOMe)
  • 2C-G-NBOMe
  • 2C-N-NBOMe
  • 2C-TFM-NBOMe
  • 25CN-NBOMe
  • 25F-NBOMe
  • 25H-NBOMe
  • 25P-NBOMe
  • 25iP-NBOMe
  • 25T2-NBOMe
  • 25T4-NBOMe
  • 25T7-NBOMe
  • Mescaline-NBOMe

Most commonly users take the substances sublingually or by snorting them. The effects vary by substance as well as administration route and dosage, with durations lasting as little as four hours with insufflation and as much as eight hours sublingually (Erowid, 2011).

Side Effects and Adverse Reactions:

Paranoia, fear, anxiety reactions, nausea, increased heart rate, chills, and insomnia are some of the negative reactions people are experiencing with this series of substances (Erowid, 2011).

Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.

Deaths Attributed to the NBOMe Series:

25I-NBOMe – In June 2012, two teens in Grand Forks, North Dakota and East Grand Forks, Minnesota fatally overdosed on 25I-NBOMe. In October 2012, a 21-year-old man from Little Rock, Arkansas also died of an apparent overdose after taking a liquid drop of the drug nasally at a music festival.

25C-NBOMe – In April, 2013, two teens in Fredericksburg, Texas, consumed a legal substance thought to be 25c-NBOMe. One of them died, and the other was hospitalized but recovered.

Other Possible NBOMe Series Deaths



Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers

Theoretical studies on the interaction of partial agonists with the 5-HT2A receptor

Molecular Interaction of Serotonin 5-HT2A Receptor Residues Phe339(6.51) and Phe340(6.52) with Superpotent N-Benzyl Phenethylamine Agonists

Synthese und Pharmakologie potenter 5-HT2A-Rezeptoragonisten

Characterization of Eleven 2,5-Dimethoxy-N-(2-methoxybenzyl)phenethylamine (NBOMe) Derivatives and Differentiation from their 3- and 4-Methoxybenzyl Analogues (DEA)

More Info:

25C-NBOMe on Drugs-Forum

Index of NBOMe chemicals on

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