25I-NBOMe (2C-I-NBOMe) is currently Schedule I in the United States. This went into effect on November 15, 2013.
Addictive Potential: Unknown
Emergency Room Visits Yearly: Unknown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: 5-HT(2A) receptor agonist
Overview: 25I-NBOMe (also known as 2C-I-NBOMe, N-Bomb, and Smiles) is a derivative of the substituted phenethylamine psychedelic 2C-I. That said, the effects are not the same as 2C-I. In fact, 25I-NBOMe is around 16 times more potent than 2C-I. It was discovered in 2003 by Ralf Heim at the Free University of Berlin, and it was subsequently investigated by a team at Purdue University led by David Nichols.
According to Erowid, “2C-I-NBOMe is active at extremely low sub-milligram doses”. The effects usually last 6-10 hours if taken sublingually or buccally. When insufflated, the effects usually last 4–6 hours.
Side Effects & Adverse Reactions:
25I-NBOMe is a very new substance, and little is known about its side effects, adverse reactions, long term damage, and/or addiction potential. Remember, research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their effects in humans. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.
In June 2012, two teens in Grand Forks, North Dakota and East Grand Forks, Minnesota fatally overdosed on 25I-NBOMe.
In October 2012, a 21-year-old man from Little Rock, Arkansas also died of an apparent overdose after taking a liquid drop of the drug nasally at a music festival.