Overview:
Methylphenidate (MPH) is an amphetamine-like prescription stimulant commonly used to treat Attention-deficit hyperactivity disorder (ADHD) in children and adults. It is also one of the primary drugs used to treat symptoms of traumatic brain injury, the daytime drowsiness symptoms of narcolepsy, and chronic fatigue syndrome.
Brand names of drugs that contain methylphenidate include Ritalin® (Ritalina®, Rilatine®, Ritalin LA® (Long Acting), Attenta®, Concerta® (a timed-release capsule), Metadate®, Methylin® and Rubifen®. Focalin® is a preparation containing only dextro-methylphenidate, rather than the usual racemic dextro- and levo-methylphenidate mixture of other formulations.
A newer way of taking methylphenidate is by using a transdermal patch (Daytrana®), similar to those used for birth control and nicotine release.
Some people abuse MPH by crushing the tablets and snorting them thus changing the typical theraputic delivery system. The "high" results from the rapid increased rate of dopamine transporter blockade due to quicker absorption into the bloodstream. When abused, the effect of Ritalin is similar to that of cocaine or amphetamine and such abuse can lead to addiction. Street names for Ritalin include: diet coke, kiddie cocaine, kiddie coke, vitamin R, R-ball, poor man's cocaine, rids, skittles, R-pop, baby blow, coke junior and smarties.
Research:
Effects of Long-term Ritalin Use (pdf) - K. Cole (2007)