Overview:
5-MeO-DMT is a very powerful psychedelic tryptamine. It is found in a wide variety of plant species and the Bufo Alvarius toad, and like its close relative DMT, it has been used as an entheogen by South American shamans for thousands of years.
5-MeO-DMT was first synthesized in 1936. In 1959, it was isolated as one of the psychoactive ingredients of Anadenanthera peregrina seeds used in Yopo snuff. It occurs in many organisms that contain bufotenine (5-hydroxy-DMT), and is the O-methyl analogue of that compound.
It is active when smoked, insufflated, injected IV, or combined with an MAOI.
Currently, Nebraska and South Dakota have classified 5-MeO-DMT as Schedule I at the state level.
