AMTAlphaMethylTryptamine

 

AMT (Alpha Methyl Tryptamine) is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute (sell, trade or give) without a DEA license. Not available by prescription.

Addictive Potential: None

Emergency Room Visits Yearly: A handful of hospital visits, 2 verifiable deaths from overdose more...

Mandatory Minimum Sentence: ??

Mechanism of Action: Increases the Neurotransmitter Serotonin

Overview:

α-Methyl-tryptamine, also known as alpha-methyltryptamine, α-MT, AMT or IT-290, is a synthetic drug of the tryptamine family. It was described in Shulgin’s book TIHKAL (Tryptamines I Have Known And Loved). According to Shulgin, "In the 1960's there was quite a bit of interest at a couple of pharmaceutical houses in the indole analogues of amphetamine. Both the alpha-methylated tryptamine (AMT) and the alpha-ethylated homologue (AET) were found to be effective monoamine oxidase inhibitors, and both were clinically studied as potential antidepressants. The ethyl compound became a commercial drug, offered by the Upjohn Company as Monase, but now is considered to be without medical use and is a Schedule I drug. It is interesting that this methyl compound, AMT was also a medically available antidepressant in the Soviet Union in the 1960's and was sold under the name of Indopan, in 5 and 10 milligram tablets."

Like many other tryptamines, at sufficient dosages it is a psychedelic entactogen. Users may experience empathogenic and entheogenic effects. The duration of effects from 20 mg of AMT usually last between 8 and 14 hours.  Its effects may take 2 hours to onset. It also acts as a monoamine oxidase inhibitor (MAOI) and a stimulant.

On 4 April 2003, an emergency United States DEA order resulted in α-MT being placed, along with 5-MeO-DIPT, on Schedule I of the Controlled Substances Act.

AMT is chemically related to serotonin, an important neurotransmitter. It acts by mimicking the effects of serotonin at the 5-HT2 receptor and by interfering with neurotransmitter reuptake and degradation mechanisms. α-MT has a stereocenter, and S-(+)-α-MT is the more active stereoisomer.

 

Side Effects and Adverse Reactions:

Users may experience increased energy, empathy, euphoria, hallucinations, emotional distress, anxiety, dilated pupils, jaw clenching, nausea, headaches, vomiting, and diarrhea.

FIU Student's February Death Linked To AMT: A 22-year-old frequenter of clubs has died from a new drug on the scene called AMT. Police said in February, 22-year-old Dan Arango, sweating profusely and trembling, told his roommates he had discovered the secrets of the universe. Then the Florida International University student went to sleep and never woke up. His father spoke Monday, saying his son's death hurts a lot especially when he thinks he was only 22 years old. Police said Arango got the drug over the Internet and that it's often passed off as the club drug Ecstasy. Drug experts say they do not yet know the full dangers of AMT. Arango is the first person in Miami-Dade County to die from taking AMT (NBC6, 2003).

Bay County Death: Authorities in Bay County are hoping to learn today what kind of drug killed 21-year-old Felicia Staats. Detectives say a new drug called AMT is being sold as Ecstasy. It's believed that Staats died after taking the pills Sunday night. Jason Clewis, who also took the same drug, was found in "what appeared to be a daze" and nearly died from taking the same substance. Authorities say the pills appear to be a popular form of Ecstasy known as "Blair Witch." Investigation continues in the case (WTVY, 2003).

 

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