Overview:
DMT, or N,N-dimethyltryptamine, is an entheogen that has been used in a spiritual setting for millennia. In South America two churches, the Santo Daime and União do Vegetal, use ayahuasca, or hoasca, as their sacrament. This is a tea made from boiled plants. One plant contains DMT and another plant contains MAOIs, or monoamine oxidase inhibitors. DMT is only orally active when it is combined with an MAOI.
In the United States, DMT is classified as an illegal Schedule I drug. For a drug to be classified as Schedule I it has to fit into these categories:
(A) The drug or other substance has a high potential for abuse.
(B) The drug or other substance has no currently accepted medical use in treatment in the United States.
(C) There is a lack of accepted safety for use of the drug or other substance under medical supervision.
Despite the fact that DMT is classifies as a Schedule I drug, the United States Supreme Court recognized it's spiritual significance. In Gonzales v. O Centro Espirita Beneficente Uniao do Vegetal, the Supreme Court heard arguments on November 1, 2005 and unanimously ruled in February 2006 that the U.S. Federal Government must allow the União do Vegetal to import and consume ayahuasca for religious ceremonies under the 1993 Religious Freedom Restoration Act.
Pure DMT at room temperature is a clear or white crystalline solid. DMT was first chemically synthesized in 1931. It occurs naturally in many species of plants.
DMT is active without an MAOI if it is smoked, snorted, inserted into the anus, or injected.
Research:
Effects of DMT in Humans
Hallucinogen Persisting Perception Disorder: what do we know after 50 years?
Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids
A general screening and confirmation approach to the analysis of designer tryptamines and phenethylamines in blood and urine
E-books:
DMT: The Spirit Molecule - by Rick Strassman
Trip Reports:
The DMT Chronicles: Traversing Beyond the Psychedelic
