MDMA is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute (sell, trade or give) without a DEA license.
Addictive Potential: Low
Emergency Room Visits Yearly: 2,221 in 2003 more...
Mandatory Minimum Sentence: 6 years for 800 pills
Mechanism of Action: Increases the Neurotransmitters Dopamine, Norepinephrine, and Serotonin
Overview:
MDMA (3,4-methylenedioxymethamphetamine), or ecstasy, is an entactogen that has gained popularity over the past 20 years because of its ability to produce strong feelings of comfort, empathy, and connection to others.
MDMA inhibits the reuptake of serotonin and it reverses the action of the transporter so that it actually begins pumping serotonin into the synapse from inside the cell. This usually causes the serotonin storage vesicles to be emptied after only a few hours with a standard recreational dose.
In addition, MDMA has a partial affinity for blocking the reuptake of dopamine and a smaller affinity still for blocking that of norepinephrine as well as other neurotransmitters in smaller quantities. The former two neurotransmitters, amongst others which may also be released in small amounts, are responsible for increased energy and contribute to the "speedy" feeling of the drug experience, whereas serotonin contributes primarily to feelings of well-being, euphoria, and decreased hostility.
The empathic action of MDMA is yet to be understood well, but one theory is that oxytocin, a hormone and neurotransmitter crucial to social bonding, is released in large quantities when MDMA is taken.
It most frequently comes in tablet form, although it is occasionally sold in capsules or as powder. It is most frequently used orally and rarely snorted. MDMA use is closely tied to the underground rave scene throughout the world, but has also been widely used by therapists as an adjunct to psychotherapy. more...
Video: MDMA - The Experience & How to Ease the Back-End
Nutrients for Blocking Phenethylamine Damage:
Nutrient
Preventive Dose
Therapeutic Dose
Form
b-Carotene
5 mg
15 mg
Consider supplements of other carotenoids (e.g., lycopene) as they become available
Bioflavonoids
2 grams
6 grams
Mixed bioflavonoids from a variety of sources
Coenzyme Q10
100 mg
300 mg
Only one form available
L-Ascorbic acid
2-4 grams
6-12 grams
Free acid or calcium, magnesium salt
L-Carnitine
1 gram
3 grams
L-carnitine HCl or, if possible, less hygroscopic salts (e.g., L-carnitine magnesium citrate)
N-Acetylcysteine (NAC)
2 grams
6 grams
Only one form available; do not use L- cysteine
Selenium
250 mcg
500 mcg
Form not critical -- inorganic (e.g., selenite) as effective, and less expensive, than organic forms (e.g., selenomethionine)
Vitamin E
1,000 IU
3,000 IU
Available data indicate that form is not critical
* From Phenethylamines, Free Radicals, and Antioxidants by Brian Leibovitz, Ph.D.
Nutrients for Helping the MDMA Back-end (week after):
