Overview:
Peyote (Lophophora williamsii) is a small button shaped cactus 2-5 inches in diameter, which grow in Mexico and the Southwest United States. Peyote is a hallucinogen, or entheogen, that is traditionally dried and eaten in a ritual setting to induce spiritual visions.
From earliest recorded time, peyote has been used by indigenous peoples, such as the Huichol of northern Mexico and the Navajo in the southwestern United States, as a part of traditional religious rites. In the late 1800s, the tradition began to spread northward as part of a revival of native spirituality under the auspices of what came to be known as the Native American Church, whose members refer to peyote as "the medicine", and use it to combat alcoholism and other social ills. The Native American Church is one among several religious organizations that can legally use peyote as part of their religious practice.
A resurgence of interest in the use of peyote was spawned in the 1970s by accounts of its use in the early works of writer Carlos Castaneda. Don Juan Matus, the pseudonym for Castaneda's instructor in the use of peyote, used the name "Mescalito" to refer to an entity that purportedly can be sensed by those using peyote to gain insight in how to live one's life. Later works of Castaneda asserted that the use of such psychotropic substances was not necessary to achieve heightened awareness and de-emphasized the use of peyote as a general means to achieve this end. Castaneda's writing has been largely discredited as serious anthropological research and is generally considered to be allegorical fiction.
Research:
Psychological and Cognitive Effects of Peyote Use Among Native Americans by John H. Halpern, MD
Hallucinogen Persisting Perception Disorder: what do we know after 50 years? by John Halpern MD
