Addictive Potential: None
Emergency Room Visits Yearly: Unkown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: blocks the neurotransmitter acetylcholine, muscarinic receptor (M1) antagonist
Scopolamine, known by the names levo-duboisine and hyoscine, is a tropane alkaloid drug that has anticholinergic properties and muscarinic antagonist effects. It is obtained from plants such as belladonna, brugmansia, henbane,mandrake, and datura.
Scopolamine has legitimate medical applications in very minute doses. As an example, in the treatment of motion sickness, the dose, gradually released from a transdermal patch, is only 330 microgrammes (µg) per day.
Side Effects and Adverse Reactions:
The common side effects are related to the anticholinergic effect on parasympathetic postsynaptic receptors: dry mouth, throat and nasal passages in overdose cases progressing to impaired speech, thirst, blurred vision and sensitivity to light, constipation, difficulty urinating and tachycardia. Other effects of overdose include flushing and fever, as well as excitement, restlessness, hallucinations, or delirium. These side effects are commonly observed with oral or parenteral uses of the drug and generally not with topical ophthalmic use. An overdose can cause delirium, delusions, dangerous elevations of body temperature, stupor and death.